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Ary lung cancers and paired brain metastases. In renal cell carcinoma, there was discordance in tumor cell PD-L1 expression between 20.eight of the paired primary and metastatic lesions [26]. In addition, brain metastases in melanoma had few TILs [27], that is concordant with our findings demonstrating that the majority of the brain metastases had been immunologically ignorant due to the lack of

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