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Hat anthrax vaccine protects regardless of route of exposure.3 The modern military safety surveillance system first identified the rare risk of myopericarditis after smallpox vaccination,4 something otherwise unrecognised in America, and then described the extent of recovery from this condition.5 The rigorous screening programme adopted in the US civilian and military smallpox vaccination program
C, d).ALDH1 expression in tumor cells is not independent risk factor for overall survivalMultivariate analysis was performed using Cox Regression method based on the above clinicopathological parameters and ALDH1 expression in tumor cells and stromal cells (Table 4). Age at diagnosis, FIGO stage and differentiation grade are independent risk factor for overall survival in ovarian carcinomas (p
Is still the most lethal gynecologic malignancy worldwide. Although most ovarian carcinoma cells are initially sensitive to chemotherapy, there is always a small population cells that always survives and initiates new tumors which causes recurrence [31]. The verification of tumor heterogeneity further enhances the hypothesis of CSCs. Compelling evidence has shown that ovarian carcinomas with enri
Lignant potential in tumors. Well differentiated carcinomas are regarded as low malignant potential and conversely poor differentiated carcinomas as high malignant potential in ovarian carcinomas [26]. In the well differentiated carcinoma group the percentage of ALDH1 high expression cases in tumor cells (31.6 ) was much higher than the percentage in the moderate differentiation group (11.3 ) a
The rise of CSC theory, some specific CSC markers were being discovered to identify putative CSCs, and ALDH1 is becoming to act as a CSC marker in the CSC studies of variable tumor types in vitro and in vivo. Epithelial-to-mesenchymal transition (EMT) is an important driver of tumor invasion and metastasis, which may be a feature of CSC. Compared to ALDH1(-) EMT cells, only ALDH1(+) EMT cells had

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